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The Benefits of Pyuria in Children
When we published the 2011 guidelines we weren't clever enough to talk about it as the two step method. Kathy Shaw and Jane Levelle at CHOP showed not only was it practical in their ER, but it reduced the number of catheterizations by more than a half from 63% to less than 30%. So it is practical. It does save kids the catheterizations and whether we're missing something if we are a tan, very low weight. If you want to increase your sensitivity because this is a screening test for who are we going to catheterize and get a urine culture then the highest sensitivity is going to be with any leucoside esterase.