How to Make a Breakthrough Intentionally

In quantum theory in fundamental quantum theory it's just not there anymore at least not if you adopt the Everett interpretation. So when people make breakthroughs intentionally instead of accidentally or by working on something else is that or how random is that? I don't know this is really a question about psychology because it's saying like what would you do instead well instead you would work on what's interesting and but if you're interested in how to feed the world rather than in you could be interested in plants, for example.