Unraveling Lewy Pathology Insights

This chapter explores a groundbreaking study analyzing 173 unique postmortem cases of Lewy pathology without prior symptoms. Researchers utilize an extensive dataset to investigate early stages of Lewy body disease and apply a machine learning algorithm, Sustain, to categorize different subtypes of pathology. The discussion highlights the clinical implications of distinguishing between brain-first and body-first manifestations, aiding in the understanding of symptoms and potential precision medicine approaches.