Ali Safie is the inventor of this hiccup remedy called Hicaway. He's also a professor of neurosurgery at the University of Texas Health Center in San Antonio. Ali started working on hiccup treatments because he was seeing lots of patients who had strokes and couldn't stop hiccuping. Most of these home remedies, either they're working on the frantic nerve or vagus nerve - two nerves that control our diaphragm muscle and control our throat.