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#202 – Rick Doblin: Psychedelics

Lex Fridman Podcast

CHAPTER

MDMA and PTSD: A Clinical Breakthrough

This chapter explores a pivotal phase three study on MDMA as a treatment for PTSD, discussing the extensive research and trial phases required to develop effective psychedelic therapies. It highlights the challenges of conducting double-blind studies and maintaining anonymity among participants while examining the safety and efficacy of MDMA compared to traditional SSRIs. Insights from the study also reveal the complexities of therapeutic experiences and the unexpected effects of placebos in treatment settings.

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