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#87 - Rick Johnson, M.D.: Fructose—The common link in high blood pressure, insulin resistance, T2D, & obesity?

The Peter Attia Drive

CHAPTER

The Evolution of Fruit and Uric Acid Metabolism

This chapter investigates the dietary significance of fruit for animals, especially before hibernation, and its evolutionary implications for ancient fossil apes. It highlights a crucial mutation in uric acid metabolism that enabled these apes to adapt to cold climates, ultimately linking their evolutionary journey to modern humans. The discussion extends to the contemporary health impacts of uric acid, including its connections to gout and metabolic disorders influenced by fructose consumption.

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