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53. Calcium Pyrophosphate Deposition (CPPD)

ACR on Air

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The Risks of CPPD

With dual energy CT, you can certainly distinguish monosodium urate crystals from calcium pyrophosphate crystals. And how about an ultrasound? Is it usually easy to distinguish uric acid? Yeah, yeah. As we call it, CPPD pseudo-Gout. This is called the pseudo-double contour sign in CPPD. So the location of these deposits is different. It's not quite as linear as it would be for MSC. The CPP crystals certainly cause mechanical damage to the cartilage and there are also local inflammatory factors from these crystals that can damage cartilage.

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