Understanding SNPs and Disease Associations

This chapter explores single nucleotide polymorphisms (SNPs) and their significance in genetic research, particularly for diseases like type 2 diabetes. It discusses the methodologies behind genome-wide association studies (GWAS) and the challenges posed by statistical variability and linkage disequilibrium. Through a detailed examination of SNP variation and its implications for health outcomes, the chapter highlights tools and strategies to connect genetic variations to gene expression and disease regulation.