When nicotine gets into the bloodstream, it's making us more alert. It's preparing our body for readiness. The heart is pumping harder. Epinephrine, that is adrenaline, is released from the adrenal glands,. So everything is pointed toward creating more readiness to move more readiness to think. And again, this is happening in parallel with all the effects of neurochemistry that are happening with the brain. But when people ingest nicotine acutely, and let's say they do that by Nick Rhett Patch or by toothpick dipped in nicotine, it will have some of these same effects.

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