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Prophylactic Antibiotics in Severe Alcohol-Related Hepatitis, Autotaxin Inhibitor Ziritaxestat for Idiopathic Pulmonary Fibrosis, Review of Cirrhosis, and more

JAMA Editors' Summary

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Cirrhosis and Its Complications

The most common causes of cirrhosis in the U.S. include alcohol use disorder, non-alcoholic fatty liver disease, and hepatitis C. Cirrhosis can be diagnosed by liver biopsy, but may also be diagnosed non-invasively. First-line therapies include carvatalol or propranolol to prevent ferricile bleeding,. lactulose for hepatic encephalopathy; combination aldosterone antagonist and loop diuretics for ascites. turlopressin for hepato renal syndrome.

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