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The Skeptics Guide #1026 - Mar 8 2025

The Skeptics' Guide to the Universe

CHAPTER

Exploring TIGR: The Future of Genetic Engineering

This chapter investigates the emerging genetic engineering technique TIGR, highlighting its advantages over CRISPR, particularly its ability to operate without PAMs. The discussion emphasizes the discovery process and the implications of TIGR's features, such as reduced off-target effects and smaller protein size for enhanced delivery. Additionally, it explores the potential applications of TIGR in therapeutic settings while contrasting it with traditional gene editing and silencing methods.

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