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What’s the difference between the NADH/NAD+ and the NADPH/NADH ratios? | Masterjohn Q&A Files #179

Mastering Nutrition

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The Difference Between the NADH to NAD Plus Ratio and the NADPH to NADH Ration

Chris Masterjohn is a PhD in Nutritional Sciences. The NADH to NAD ratio and the NADPH to NADP plus ratio are biochemically relevant but have no biochemical relevance, he says. Niacin deficiency will selectively deplete the pool of NADH first so that's one marker of nutritional status. If you're overfed sedentary those two ratios are signifying the same thing: your body isn't working properly.

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