Enzymes in Serologic Study

When we're using enzymes in our serologic study, what we're doing is taking fairly common proteases. The negative charges kind of keep the red cells apart from each other. So when we have something that shaves off these structures that are carrying much of the negative charge, then it allows the red cells to get closer together. And so you can get some antibodies showing up a little bit stronger because the antibody and antigen reaction can take place.