3min chapter

The Immunology Podcast cover image

Ep. 35: “Inflammatory Bowel Disease” Featuring Dr. Karen Edelblum

The Immunology Podcast

CHAPTER

The Microbiome and Metoplastic Gastroids

The cytokine IL 23 accelerates what's called spama to explain in a second, maturation and proliferation in mouse normal and metoplastic gastroids. Spama is essentially a metoplastic slash precancerous state in gastric tissue that's been really recently described. It's actually interesting because we think of it base level of test on biology. There's not that much difference between the stomach and the colon and everything in between,. But a metplastic state's been described in the gastric tissue, but not in the colon tissue before cancer.

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