Navigating the Challenges of Conducting a Psychedelic Study

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The chapter delves into the initial stages of a research project focused on psychedelics, detailing the hurdles of regulatory issues and fundraising with the aid of mentors. It describes the excitement and anxiety of the first dosing session with a team member, highlighting the dedication and logistical challenges faced. The chapter also examines the evolving landscape of psychedelic research, emphasizing resilience, societal learning, and the importance of creating a supportive setting for participants in therapy.

In this episode, Joe interviews Dr. Robin Carhart-Harris: founder and head of the Centre for Psychedelic Research at Imperial College London, founding director of the Neuroscape Psychedelics Division at University of California, San Francisco (UCSF), and founder of the Carhart-Harris Lab.

A legendary researcher, he talks about his psychedelic origins: studying Freud, Jung, and eventually Stan Grof and depth psychology to try and better understand the unconscious. He discusses the growth of psychedelics and the cultural shifts he’s noticed (especially in the U.S.), as well as what he’s working on today: researching the influence of psychedelics on set and setting by studying experiences in both enriched and unenriched environments.

He also talks about:

Plasticity: how he defines it, how it relates to critical reopening periods, and how it’s a fundamental thing that transcends the metrics we use to measure it
Early LSD studies, the nervousness surrounding he and David Nutt dosing Ben Sessa, and the youthful energy that kept them going
How plasticity could be exploited to help relieve chronic pain
The potential of psychedelics to help with fibromyalgia and anorexia
How psychedelic-assisted therapy brought care back to health care

and more!

UCSF is seeking survey volunteers, so if you’ve had more than three experiences with ketamine, MDMA, and psilocybin (must have experiences with all three) and want to contribute, do so here. Click here to head to the show notes page.