What Happens When You're in Space?

"What happens to people when they're in space? We know that there are some short term things that happen, right?" he asks. "We haven't looked at why and the astronauts keep telling us not to worry about it." And what we want to know is if we send you out there for a year, yeah, five years, 10 years, half your life, will we recognize you when you get back? Or will you be a bunch of tentacles just like Neil Armstrong was"? He goes on to discuss his favorite sci-fi movie with Oscar Isaac called Annihilation.