Time Stamps:
00:00:00 - Peter Attia’s new book ‘Outlive’
00:02:26 - Who is Peter Attia? What is Medicine 3.0?
00:03:28 - Peter Attia’s career. How did he become a doctor? And how did he evolve into his unique approach to preventative medicine?
00:07:54 - What do the acronyms in Peter’s Instagram bio stand for?
00:13:53 - The Four Horseman of Death (most will die from one of these)
00:22:46 - How to not die from atherosclerotic disease (the leading cause of death)
00:29:59 - The impact of smoking on atherosclerotic disease
00:30:36 - The impact of high blood pressure (hypertension) on atherosclerotic disease, how common it really is, and how to track it
00:32:32 - The accuracy of manual vs. automatic blood pressure cuffs
00:35:41 - The impact of APOB/all atherogenic particles (LDL’s, LP(a)’s, VLDL’s, and IDL’s) on atherosclerotic disease
00:40:57 - The minimum APOB level needed for adequate function
00:42:43 - PCSK-9 gene and its effect on LDL. How PCSK-9 inhibitors work to lower LDL
00:43:24 - APOB vs. APOA
00:44:56 - The most effective lipid managing dr*gs for preventing atherosclerosis
00:50:16 - Why Peter doesn’t see a reason why anybody should have an APOB over 60 mg/dL
00:52:15 - If Peter could go back in time knowing what he knows now and with modern pharmacology, at what age would he start lowering his APOB
00:55:04 - Arterial plaque accumulation starts as early as when you are a teenager. Calcification takes years to show up on a coronary CT calcium scan, but that does not mean plaque isn’t accumulating
00:57:12 - Should you screen for atherosclerosis before taking medication? If so, how?
01:01:06 - Why are carnivore diet zealots so dogmatic about cholesterol and atherosclerosis? What does the data show to date?
01:06:05 - If those with average genetics maintain a near perfect diet, exercise regimen and sleep hygiene, will many of those individuals still develop atherosclerosis?
01:09:41 - How to lower blood pressure
01:13:25 - Sleep Apnea and the use of CPAP
01:16:49 - Cancer: Causes, Prevention, and Proactive Screening
01:35:53 - The devices and metrics Peter uses to track his sleep and recovery
01:41:50 - Resting heart rate, HRV, heart rate recovery, and how predictive they are of mortality
01:44:43 - Peter's full daily routine and diet
01:54:35 - Why Peter stopped fasting
01:57:12 - Bodybuilders abuse of T3, Clen, DNP, and other metabolic modulators
01:58:54 - Peter breaks down his 6000+ calorie diet, 6 hours of daily exercise, and the most absurd meals he ate to maintain his weight when he was younger
02:01:25 - How Peter’s kids eat. How strict should the diet be for your kids when it comes to food quality to maximize growth potential?
02:07:41 - Where is the best burger in Austin?
02:08:22 - What time Peter stops eating each night, and the hack he uses to prevent him from overeating
02:11:33 - Peter's non-negotiable nightly practices for maximizing sleep quality
02:12:31 - Why Peter has a Bat phone
02:14:29 - How to live in the moment and be happy. The vicious circle of financial success and/or accolades never being enough.
02:22:46 - How to decide if you should have kids
02:25:13 - Peter’s Top 10 Supplements and Top 10 Dr*gs
02:29:35 - Peter's personal supplement stack and dr*g protocol
02:42:26 - Homocysteine reduction protocol
02:44:11 - Vitamin B6 deficiency paradoxically caused by Pyridoxine Hydrochloride supplementation
02:46:00 - How safe is TRT for cardiovascular health? TRAVERSE clinical trial results
02:51:31 - Comparison of TRT administration methods. What Peter prefers for patients
02:52:40 - What podcasts and YouTube channels Peter likes to watch or listen to
02:55:09 - Formula 1
02:55:54 - AlphaTauri x Hugo Boss
02:56:21 - Daniel Ricciardo, Max Verstappen
02:59:33 - How Red Bull became such a dominant F1 team
03:01:35 - Sim racing
03:05:13 - How Peter got so interested in F1
03:06:33 - Peter’s dream car
03:06:50 - Ayrton Senna
03:08:25 - Outro
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