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#05 Matt Kaeberlein | Aging Interventions - Rapamycin, mTOR, CR, Sirtuins, NAD+ & Dog Aging Project

Live Longer World

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Is There Evidence to Support the Effects of Caloric Restrictions in Mice?

There isn't, there is no generalization that I would say is fair in terms of the quality of the diet or the composition of the diet. The thing that does seem, I think pretty compelling to me is the idea that at least part of the effects of caloric restriction require a prolonged fasting period. There's a really interesting paper from Dudley Lamming that just came out that supports this. But if you go back and look, people have been saying this for a long time,.

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