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This mysterious space rock shouldn’t have a ring — but it does

Nature Podcast

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Repurposing a Skin Disease Medication to Treat Alcohol Use Disorders

A Premelast is licensed in the US to treat the skin disease psoriasis. It works by inhibiting an enzyme linked to alcohol dependence. The team injected a Premelast into mice that were bred to drink heavily. They noticed the rodents had lower alcohol levels and did not binge drink as much as animals receiving a placebo. In humans, adults with alcohol use disorder who took the drug daily had fewer drinks per day over an 11 day period than those who took a placebo. With further studies the drug could be used more widely for the treatment of alcohol use disorders.

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