Limits of the amyloid hypothesis

By the time memory begins to slip, the changes affecting the brain may have been developing for decades. But the trajectory isn’t fixed, and many of the factors driving it are within our control.

In this episode, I sit down with my longtime friend and mentor Dr. David Perlmutter, six-time New York Times bestselling author whose new book, Brain Defenders, rethinks what it really takes to protect the brain as we age.

You’ll learn:

• Why protecting your brain should begin long before memory problems appear

• How your daily choices influence whether the brain’s immune cells shift into a protective or damaging state

• Which numbers to know now, including fasting insulin, blood sugar, and waist-to-hip ratio

• How food, exercise, sleep, gut health, and environmental toxins shape your brain’s future

• What emerging research reveals about slowing—and even improving—cognitive decline

I’ve always appreciated how David’s work replaces fear with something far more useful: a clearer understanding of how the choices we make today can help protect our memory, independence, and quality of life for years to come.

View Show Notes From This Episode

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