Is Cranninine a Good Marker for Acute Kidney Injury?

In this conversation, Daniel Belkin and Mitch Belkin speak with Joel Topf, MD, about contrast-associated nephropathy. We discuss Acute Kidney Injury (AKI), the value of creatinine as a marker for AKI, how to evaluate volume status, the evidence around contrast-induced/contrast-associated nephropathy, recommendations on fluids to prevent AKI in patients with Chronic Kidney Disease, and comparing venous and arterial contrast with respect to the risk of AKI.

Who is Joel Topf?

Dr. Topf is a clinical nephrologist in Detroit, who is a partner and medical director at St Clair Nephrology and an assistant professor at Oakland University William Beaumont School of Medicine. He is the co-creator of NephMadness and NephJC. He hosts multiple podcasts, blogs at pbfluids.com, and tweets @Kidney_boy. 

References: 

• Joel Topf’s Blog 
• Twitter: @Kidney_Boy
• Joel Topf - Grand Rounds Presentation on Contrast Nephropathy
• The PRESERVE trial
• N-Acetylcysteine and Contrast-Induced Nephropathy in Primary Angioplasty
• Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate
• Craig Brater 1998 - NEJM review on Diuretics
• Chlorthalidone for Hypertension in Advanced Chronic Kidney Disease
• Effect of Salt Substitution on Cardiovascular Events and Death

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What is the External Medicine Podcast?

The External Medicine Podcast explores some of the most exciting ideas in medicine. Co-hosted by Daniel Belkin, MD, and Mitch Belkin, MD.

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