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The Theory of Knowledge Works by Making Connections Between Things
There's nothing new under the Sun, David. Everything is just making connections between existing stuff. Most rearrangements of characters are not new explanations. So you can either change a theory slightly in the hope that the rest of it still works or you can make new combinations between things. You can either have cosmic rays strikes a DNA and changes one base pair or something, or you can have some error in copying results in a bit of DNA from somewhere else being stuck into a particular place in the DNA strand.