Effects of Metformin on Muscle Mass and Hormone Levels

Metformin is one of the oldest and most studied drugs on earth, but a lot of people in the medical community are still hesitant to prescribe it. What are the benefits of this drug for people with different health problems and needs? What does it do for weight, insulin levels and high blood sugar? Does it make people hypoglycemic? On this episode, Dr Nelson Vergel gives a presentation on different studies of metformin and why it’s a great drug to use.

Testosterone-metformin combination therapy decreased total and LDL cholesterol, uric acid, hsCRP, homocysteine and fibrinogen, and it increased plasma testosterone. -Dr. Nelson Vergel

Three Takeaways

1. Metformin shifts gut bacteria and gives patients the gut biome composition of a leaner person.
2. Metformin doesn’t decrease blood sugar to hypoglycemic level.
3. In HIV positive patients, studies have shown a reduction in T-cell exhaustion with the use of metformin

At the start of the show, we talked about why metformin is such a hot topic right now, and Dr. Nelson began his lecture on metformin, starting with its history, benefits and some of the reasons why it causes patients to lose weight. We also discussed its benefit for people with cancer, and overweight people. Towards the end of the show we talked about what people get wrong about the ketogenic diet.

We also discussed;

• How metformin affects the gut biome
• Metformin’s impact on HIV positive patients
• Why metformin is better than berberine
• Metformin and diabetic mortality rates

Metformin is a hot topic right now, and with good reason. It has a lot of benefits, it is affordable and it has a great many studies backing it up. It dilates vessels, it decreases insulin and blood sugar, it improves metabolism of glucose, cardiovascular protection and it also decreases weight and lipids. Testosterone and metformin work very well together when it comes to body composition and inflammation. Metformin has also shown an ability to increase lifespan for people with cancer, and it helps people with HIV a great deal. There no risks with metformin unless you have some sort of renal issue, or take a drug with a contra-reaction.  If you’re going to start taking, it start low, and go slow.

Guest Bio-

Nelson Vergel is a chemical engineer who, by his own necessity, has become a leading advocate for sports nutrition, supplementation, hormone and therapies, and the promotion of wellness. His search for cutting-edge health  knowledge started when he was diagnosed with HIV over 25 years ago during a hopeless era. This life-threatening diagnosis propelled him to explore therapies to save his life and that of his peers by reviewing available literature, attending numerous health conferences, becoming an advocate member of NIH research committees, moderating online groups, and networking with many progressive clinicians. With his survival knowledge he has been able  to help people to lead a healthy life regardless of their health status or background. He is the author of "Testosterone: A Man's Guide" and co-author of the book "Built to Survive"; the founder of the nonprofit organizations Body Positive Wellness Clinic and Program for Wellness Restoration; the Nutrition and Exercise forum expert at TheBody.com; and a bilingual speaker on body composition, exercise, nutrition, supplementation, testosterone replacement, metabolic disorders, and medication side effect management. Go to excelmale.com for more information.

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