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Reboot - Diuretics, leg cramps, and resistant hypertension

The Curbsiders Internal Medicine Podcast

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SGLT2 Inhibitors - What Are They?

If we had an effective diuretic that would shut it down in the same way that fisci-ed shuts down the distal convoluted tubule, or ferrosemide or loop diuretics shut down the loop, we would be dead. It's just because there's just so much happening, two thirds of filtration is reabsorbed. There's a huge major metabolically active area. So we have these areas of the tubules. We have our loop diuretical that are going to work on the loop of Henley. And then you've got your osmotic diuretics, manatol, which really act throughout the entire kidney and S

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