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Ep. 10: “Viral Pathogens” Featuring Dr. James Crowe

The Immunology Podcast

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Role of T Cells in Tumors and Anti-Tumor Response

This chapter delves into two papers focusing on the role of T cells in tumors, specifically looking at exhausted T cells in melanoma patients and their response to different antigens. Researchers analyze T cell specificity against tumor antigens and highlight the importance of targeting tumor-specific T cells for effective treatments. They also discuss unique approaches like using bispecific antibodies to recover exhausted T cells and the challenges of rejuvenating these cells due to their epigenetic changes.

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