#78 – New Therapies in HIV: The Long Road to Long-acting Antiretrovirals - Are We There Yet?
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Oral Rilpivoring and the Adverse Effects
We've actually we did the oral lead in with our first few patients although we realized that two of our very initial patients on the monthly injections were on a PPI and so we actually elected to just skip the oral Lead In. We actually had a couple of patients who had worsening mental health problems when they received the injections. So it's also kind of our little test of if you take oral rilpivoring will you do okay with your irritability and mental health challenges and people have had to work through that. I also just want to underscore an adverse effect that that Jill alluded to which is that both integrase inhibitors as a class end rilp Vivoring have a
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