In this chapter, Professor Roy Taylor discusses the twin cycle hypothesis, which explains how the body deals with food and metabolism in type 2 diabetes. He focuses on the role of muscle insulin resistance, glucose storage as fat in the liver, and the buildup of fat in various organs. The chapter emphasizes the importance of understanding this hypothesis in explaining the development of type 2 diabetes.
Episode #287. Learn about type 2 diabetes from the scientist who has fundamentally changed our understanding of the disease: Professor Roy Taylor. From the twin cycle hypothesis to personal fat threshold, this conversation is an absolute masterclass in what causes type 2 diabetes and the path towards remission for those managing it.
We discuss:
- Introduction to the Twin Cycle Hypothesis & Onset of Diabetes (00:00)
- Delving into the Twin Cycle Hypothesis: Diabetes Aetiology Explained (02:25)
- Risks Associated with High Blood Glucose Levels (14:08)
- Key Factors Causing Insulin Resistance in Muscles (20:53)
- Understanding the Personal Fat Threshold in Diabetes Onset (26:14)
- Assessing the Risk Factors for Developing Type 2 Diabetes (35:07)
- Preventative Measures Against Type 2 Diabetes (41:12)
- Are Conltinuous Glucose Monitors Beneficial for Non-Diabetics? (46:54)
- Investigating the Determinants of Body Fat Distribution (50:15)
- Summary of the DiRECT Trial: Examining the Twin Cycle Hypothesis with Roy Taylor (55:50)
- Effective Strategies for Type 2 Diabetes Remission (1:15:29)
- The Role of Diet Quality in Insulin Sensitivity Improvement (1:28:54)
- Examining the Link Between Protein Consumption and Type 2 Diabetes (1:36:18)
- Incorporating Exercise into Type 2 Diabetes Remission Plans (1:38:31)
- The Possibility of Eradicating Type 2 Diabetes Societally (1:49:03)
- Understanding the Reversal of Type 2 Diabetes: Current Insights (1:52:49)
- Final Thoughts: The Prospects for Diabetes Management (1:56:04)
Learn more about Professor Roy Taylor’s work at go.ncl.ac.uk/diabetes-reversal. You can also read his books, Life Without Diabetes and Your Simple Guide to Reversing Diabetes, for more tools and education.
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Enjoy, friends.
Simon
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Simon Hill, MSc, BSc (Hons)
Creator of theproof.com and host of The Proof with Simon Hill
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