The chapter delves into the intricate connection between melatonin and dopamine, particularly in the context of sleep induction, restless leg syndrome, Parkinson's disease, and Tardive dyskinesia. Through a thoughtful analysis of dopamine levels and melatonin's impact on neurological functions, the speakers navigate the complexities of using dopaminergic agents and melatonin as treatments. The discussion explores the potential of melatonin to influence dopamine signaling, offering insights into its role in neurological disorders and the need for further research in this fascinating intersection of sleep and neurotransmission.