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Episode 36 - Neurological Toxidromes

Neurology Exam Prep Podcast

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How to Reduce Exposure to Manganese in Children

Manganese has actually presents with a parkinsonism. They can have some postoral instability, the bra cinesia, shuffling, gait action, postoral tremors. And then outside of that, maybe a little bit of hyperaphlexia, to have that increased tone and some dis functional speech. It actually has an interesting path of physiology, an a basil ganglia related to both the dat transporters and a d m t transporter, which kind is more important for divalant metals. Both are found in really high concentration in the basil ang and actually spares the substantia nagra.

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