Endogenous Retroviruses and Immune Response in Tumors

This chapter explores the impact of endogenous retroviruses on the immune response against tumors. It discusses the validation of findings in mice to humans, the use of PCR sequencing to identify immune responses in mouse tumor lines, and a transcriptomic approach in adenocarcinoma patients. The chapter also delves into the complexity of identifying transcripts and loci in the human genome and highlights the differences between histological subtypes of lung cancer.