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Key role of hepcidin in polycythemia vera, signatures of CAR T cell dysfunction, and IL-34 as a novel AML therapy?

Blood Podcast

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The Role of IL-34 in Myeloid Leukemia Difference

The binding of IL-34 to TREM2 contribute to myeloid differentiation, authors say. Authors: These interactions also reshape the properties of AML and limit propagation of leukemic cells. Remaining questions regarding the targeting of this pathway need to be addressed.

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