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Ep. 112: “The Evolution of mRNA-Based Dendritic Cell Cancer Vaccines” Featuring Dr. Zwi Berneman

The Immunology Podcast

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Advancements in mRNA Cancer Vaccines

This chapter explores the historical development and challenges of mRNA-based dendritic cell cancer vaccines, outlining their evolution from early clinical trials to recent breakthroughs. It highlights significant methodologies, including the use of electroploration to enhance mRNA transfection efficiency, and the regulatory hurdles faced in bringing these therapies to clinical application. The narrative emphasizes the importance of strategic investments and compliance in successfully translating this innovative research into effective cancer treatments.

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