FOUR Antibodies. THREE Animals. TWO Crying Haem Registrars. ONE TEST - The MAIPA. Actually maybe more than two crying haem registrars. How many antibodies are too many antibodies to have inside a lab test? One? That’s just a DAT. Two? A mere sandwich ELISA. But the Monoclonal Antibody Immobilisation of Platelet Antigens (MAIPA) - that’s not just three but FOUR separate antibodies in the same test. If somehow you’ve made it this far thinking there wasn’t enough immunohaematology for you then it’s time to join the Bloody Minded Crew as they wrestle with the most anti-bodied of tests. Oh and we look at other platelet antibody testing too.
Timestamps
00:52 - Thanksgiving in the lab
03:42 - Platelet antigens refresher
06:10 - FNAIT
10:55 - Transfusing in FNAIT
20:18 - Testing for FNAIT
26:56 - The PIFT
29:39 - The MAIPA
37:20 - Take home messages
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