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#16 Cancer, Cellular Senescence & Senolytics | Dr. Peter Adams

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Are There Any Mechanisms?

Inactivating tagene leads to a degeneration of the chromatin with age, also ina degeneration and venotypend andfunction of the cells. There aren't that many studies describing that kind of thing. These are really, youare, basically, what you have to do is, younow, you have toinactivate your geane of interest, which has no con quence in r in e, in a young mouse,. ok? And then you have to age that mouse forfor a couple of years in anticipation of getting a phenotype. Oka, and so we are doing some of those studies, but it's early days. But you can understand why, you

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