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The Effects of Quarks on the Mass of Matter
In our universe, a neutron decays to a proton, an electron, and an anti-neutrino. But if you crank down that difference by changing the mass of the quarks, then you could actually make the hydrogen atom unstable. The reason why that doesn't happen in our universe is that the electron doesn't have enough mass to combine with the proton. So that is the closest our universe has come to a failure point.