The Importance of Early Endpoints in Tumor Therapy

The early end point means that response to therapy is really important. It allows you to pivot if someone is not having the right response. The hazard rate for EFS or the SIR-Machronis-free survival is like 0.18. For those fast-growing high-risk tumors it's an excellent endpoint. iSpy 2.2, our next face of the trial will allow us to de-escalate therapy and the setting of great responses.