4min chapter

Inside Exercise cover image

Glucose metabolism, exercise and the liver with Dr David Wasserman

Inside Exercise

CHAPTER

The Complexity of Cross-Linked Proteins

The liver is loaded with nerves, it's heavily innervated by the autonomic nervous system parasympathetic and sympathetic. And I think that this is a whole domain that remains to be fully defined. So there have been some terrific studies some of which by Matthew Watt, one of your homies in Melbourne. Some and others who've shown that you have proteins that are created by the liver and they can increase during exercise. Now what they do is the purpose of these four months, whether they're just whether they have a physiological role within the context of exercise remains to be better elucidated.

00:00
Speaker 2
is it actually only 10 I didn't pick up on that it's only 10 minutes total
Speaker 1
yes so I always confuse it it's it's typically a two to three minute warm up a two to three minute cool down with a minute in between or sorry two minutes in between these hard efforts so yes start to finish warm up cool down recovery 10 minutes and we were comparing that against traditional modern intensity continuous sessions that were taking 50 minutes five zero minutes per session so you know a a five-fold lower time commitment overall and those studies extended out to 12 weeks of training the comparisons all
Speaker 2
right so when you do that what do you get similar increases in video
Speaker 1
to max yes but and so when I say yes but in our studies the average improvement in the two groups was 19 percent so roughly 20 percent over 12 weeks or almost a two met increase in b2 max again on average for the two groups obviously within the groups you have significant variability there and again over time we've learned and I think where these studies need to go you can have just because you say two things are not different statistically it doesn't mean they're the same and so you know there's larger scale studies you can do that use these non inferior orated designs where you try to say well what would be a margin of difference that would be meaningful and so I think this is where the field needs to go into some of these more robust designs where you can tease out subtle differences if they're there taking into account power sample size things like that but when we use these small proof of concept studies on average we see very similar improvements in a range of health-related markers I'm gonna let you
Speaker 2
have

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