The DSMC's Patch Trial

The DSMC was on the patch trial, and I'd like to congratulate these guys and everybody on actually completing the trial. There were many, many times during the course of the trial where we thought that they would never, never hit their enrollment targets. And I think they've downplayed how difficult it was to actually get people on board with doing the trial. So what do I think the patch trial was trying to answer? What questions were they trying to address at this time point?