Understanding Volume and Risk Definitions in Advanced Prostate Cancer

Today on the Dr. Geo Prostate Podcast, we’re joined by world-renowned oncologist Dr. Rana McKay of UC San Diego Health. With training from Harvard and Dana-Farber, Dr. McKay breaks down the evolving landscape of triplet therapy—a combination of ADT, an ARPI (androgen receptor pathway inhibitor), and chemotherapy (docetaxel)—and how it’s changing survival outcomes for men with advanced prostate cancer.

In this enlightening and practical episode, Dr. Geo and Dr. McKay discuss:

• What triplet therapy is and how it compares to doublet therapy
• The latest clinical trials and the importance of timing treatment
• How to personalize care for high- and low-volume metastatic prostate cancer
• When to escalate treatment—and when quality of life may outweigh aggressive therapy
• The role of genomic tools like the Decipher score in decision-making
• Side effect profiles, cold therapy, fasting, and integrative strategies
• Why communication and patient values should drive treatment decisions

If you or a loved one is facing a diagnosis of advanced prostate cancer, this episode offers invaluable clarity and hope.

👉 Subscribe, share, and review the podcast to help us reach more men navigating prostate cancer and aging with strength and purpose.

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Introducing The Dr. Geo Prostate Podcast Exclusive Membership

We’ll continue bringing you powerful weekly episodes to support your prostate health journey. But if you’re ready to dive deeper, the Exclusive Membership gives you more: curated transcripts, detailed show notes, expert resources, and member-only perks—all designed to help you live better with age. Join HERE [https://drgeo.com/membership]

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Thank you to our partners

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📌 Thanks for tuning in to this week’s episode.

Subscribe to The Dr. Geo YouTube Channel for more content like this and learn how to thrive as you age. [https://www.youtube.com/@DrGeoProstatePodcast] 

You can also listen to this episode and future episodes of The Dr. Geo Prostate Podcast by clicking [http://drgeo.com/]

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• XY Wellness – for prostate cancer lifestyle and nutrition - https://bit.ly/3uJPC7Z
• Mr. Happy – nutraceuticals for prostate health and male vitality
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DISCLAIMER: This audio is educational and not medical advice. The views expressed are my own and not those of my employer(s) or affiliated organizations. Use of this content is at your own risk. Geovanni Espinosa, N.D., assumes no liability for any direct or indirect consequences, including economic loss, injury, illness, or death.