Ribosome structure and A–P–E sites

DNA doesn’t “do", it instructs. In this episode of the Jack Westin MCAT Podcast, Mike and Molly walk through the central dogma, how we go from DNA → RNA → protein—and the regulation that makes different cells, well, different. Perfect for MCAT Bio/Biochem: we hit transcription, RNA processing, translation mechanics (A–P–E sites), start/stop codons, eukaryote vs. prokaryote differences, and multi-layered gene expression regulation (chromatin, transcription factors, miRNA/siRNA, ubiquitin, & more).🔑 What you’ll learnCentral dogma overview (DNA → RNA → protein)Transcription: promoter, template vs. coding strand, initiation/elongation/terminationEukaryotic RNA processing: 5′ cap, splicing (introns vs. exons, alternative splicing), poly-A tailTranslation: AUG start (Met), codons/anticodons, tRNA charging, ribosome A–P–E sites, stop codons (UAA/UAG/UGA)Eukaryotes vs. Prokaryotes: 40/60/80S vs. 30/50/70S ribosomes, coupled transcription–translation, operons (lac/trp)Regulation: heterochromatin vs. euchromatin, histone acetylation, DNA methylation, transcription factors, miRNA/siRNA silencing, post-translational mods (ubiquitin, phosphorylation)Want to learn more? Shoot us a text at 415-855-4435 or email us at podcast@jackwestin.com! 📱📌 Free Academic Advising: https://calendly.com/academic-advising-4/jack-westin-academic-advising?utm_source=spotify&utm_medium=podcast💻 Try our Chrome Extension (video solutions to every AAMC passage) https://tinyurl.com/4jw5pad8📚 Free Resources: https://jackwestin.com?utm_source=spotify&utm_medium=podcast🎓 Live Education Sessions: https://jackwestin.com/sessions?utm_source=youtube&utm_medium=podcast👨🏻‍🏫 Courses: https://jackwestin.com/courses?utm_source=spotify&utm_medium=podcast🙋 Tutoring: https://jackwestin.com/services/live-online-mcat-tutoring?utm_source=spotify&utm_medium=podcast📸 Follow Us On Instagram: https://www.instagram.com/jackwestinmcat?utm_source=spotify&utm_medium=podcast👥 Join our Facebook Study Group: https://www.facebook.com/groups/freemcatprep?utm_source=spotify&utm_medium=podcast