Is There a Creation?

The idea that there are other created intelligences or rational souls in some sense is actually already incorporated within Orthodox Christian theology. So yes, I actually don't think there's anything with a creation or like understanding of creation or God's relationship with creation that is problematic. If we consider any kind of being that spans the chasm of the biological and spiritual, like these rational animals as what's being described, it would not be too problematic if they were humans.