The Effective Statistician - in association with PSI cover image

Real-World Evidence vs. Randomized Trials: Can We Emulate Accuracy?

The Effective Statistician - in association with PSI

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Real-World Evidence vs. Randomized Trials

This chapter examines the comparison between real-world evidence and randomized clinical trials, particularly in the contexts of stroke prevention and hypertension management. It highlights specific trials, discusses the methodological challenges of emulating RCTs, and emphasizes the importance of data quality and transparency. The chapter also addresses how real-world findings can inform regulatory decision-making and improve patient care while navigating the complexities of treatment adherence and trial design.

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