2min chapter

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Even a 'minimal cell' can grow stronger, thanks to evolution

Nature Podcast

CHAPTER

The Effects of Genome Minimization on the Minimal Cell

The initial effects of genome reduction were quite large. They made these cells sick. And when we measured the fitness of that organism at the end of the experiment, and we asked basically how sick is it now? We found that it recovered all of those fitness costs over the 2000 generations. So its fitness was equivalent to the original non minimize genome. But of course the non minimal cell evolved and became fitter during the 2000 generations as well.

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