Bob Greene: The body, the brain doesn't forget where you started and it works its way very slowly over the course of one to probably five years to get you back to where you were. He says there's a biological set point that the brain has where you ought to be in terms of weight loss. Greene: We see this in animal studies all the time when we change the rat child or how many times they go on the treadmill. There's only two interventions that I am aware of that change the set point of where the brain thinks you ought tobe. One is medications. That's what we're talking about today.

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