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Depression, Serotonin, SSRIs, Psychiatry, Mental Health & Social Media | Joanna Moncrieff | 88

Mind & Matter

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The Transition From M a O to Tricyclic Drugs

The transition from m ais to tricyclic was primarily to avoid those severe side effects of the m ais, and how much of it was the effectiveness of the tricyclics. One of the driversof developing new antidopressents was er, was to find drugs that had lower side effect profiles. Other drivers, i think, are the collapse of the market for benzediasopenes after they became apparent that these drugs were dependents forming.

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