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#45 Statins: Prescribing Meds Day vs. Night Part 2 Mind the Gap Segment

Core IM | Internal Medicine Podcast

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Effectiveness of Night-Time Statin Dosing on Cholesterol Levels

The chapter delves into the benefits of taking statins at night for reducing cholesterol levels, particularly short half-life statins, aligning with the body's peak cholesterol synthesis. It explores the debate on whether the timing of statin dosing significantly impacts patient outcomes, highlighting conflicting trial results and the importance of individualized treatment plans. The discussion emphasizes the importance of patient adherence to statin medications rather than focusing solely on the optimal dosing time, especially considering the minimal difference in LDL levels and cardiovascular outcomes based on timing.

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