Implications of Mismatch Repair Status in Stage III Colon Cancer Treatment

This week, we kick off our discussion of adjuvant systemic treatment in colon cancer, beginning with Stage III colon cancer. We will review the evidence basis for adjuvant therapy as well as the two main chemotherapy regimens including duration and side effects.

Content:

- Why do we need adjuvant therapy in stage III colon cancer?

- What is FOLFOX? What is CAPOX? When do we use what?

- What is the optimal duration of therapy?

- What are the characteristics deemed high risk?

- Can we discontinue oxaliplatin early?

- What is the role of oxaliplatin in older patients?

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