Clinical Infectious Diseases - Disease by Disease

The clinician really needs to understand what they're looking for as an example my team works a lot on peripresthetic joint infection which is largely a bacterial infection and we have a publication in pressing clinical infectious diseases where we compared 16s ribosomal RNA gene PCR sequencing or targeted metagenomic sequencing based approach. The performance of the two approaches was the same but I think it's also really helpful because it's a lot simpler to do a targeted approach and a lot more cost effective than a shotgun approach. In clinical practice I think we need to sort out disease by disease when to use these tests and exactly which test to use. We are just not there yet with the data that we