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Lab Medicine Edition | CBC: Hemoglobin/Anemia (Micro, Macro, Hemolytic)

Mayo Clinic Talks

CHAPTER

Understanding Non-Heme Causes of Polycythemia

This chapter delves into the various non-heme causes of polycythemia, including factors like dehydration, hypoxic conditions, medication influences, and rare hereditary cases, emphasizing the rarity of polycythemia vera. It explores evaluating elevated hemoglobin levels in patients and the diagnostic approach for polycythemia vera, stressing the importance of the JAK2 mutation panel. The chapter also discusses criteria for hospital admission based on symptoms, the frequency of phlebotomy, and the significance of differentiating between heme and non-heme causes through tests like JAK2 mutation analysis.

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