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3min chapter
Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity
Huberman Lab
The Monoamine Hypothesis of Depression
Mono amines are neurotransmitters, meaning they change the activity of neural circuits in the brain and body. Mono amines include things like serotonin, dopamine, and norepinephrine. The mono amine hypothesis of depression is really centered around the idea that it is deficiencies in these mono amines which give rise to depression. Drugs designed to increase certain mono amines only work in about 40% of depressed people who take them; 60% don't respond at all.
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